Dissecting and modeling the emergent murine TEC compartment during ontogeny

Fabian Brunk, Chloé Michel, Tim Holland-Letz, Alla Slynko, Annette Kopp-Schneider, Bruno Kyewski, Sheena Pinto
2017 European Journal of Immunology  
Supporting Information Figure 2 (A) Expression of Aire as a surrogate marker in MHCII hi CD80 hi , but not in MHCII hi CD80 -TECs during emrbyonic development. Results are representative of two to three independent experiments performed at the indicated time-points. Measurements for each experiment were based on 4-10 pooled embryonic or 2 adult thymi. (B) Representative dot plots of cell cycle analysis on E14.5 TEC subsets using Ki67 and DAPI. Cycling cells were defined as being Ki67 int/high
more » ... d DAPI + 2N, comprising G2/M-and S-cell cycle phases.
doi:10.1002/eji.201747006 pmid:28439878 fatcat:tkaaneg7ira6fduncfesr4u4va