Multiple Contrast Tests for Multiple Endpoints in the Presence of Heteroscedasticity

Mario Hasler
2014 The International Journal of Biostatistics  
AbstractThis article describes an extension of multiple contrast tests to the case of multiple, correlated endpoints. These endpoints are assumed to be normally distributed with different scales and variances. Unlike in previous articles, the covariance matrices are also assumed to be unequal for the treatment groups. Approximate multivariate
doi:10.1515/ijb-2012-0015 pmid:24516005 fatcat:5zfmqxrsofbyvhpcfpgdpg6dbm