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Pluripotent Stem Cells for Transgenesis in the Rabbit: A Utopia?
2020
Applied Sciences
Pluripotent stem cells (PSCs) possess the following two main properties: self-renewal and pluripotency. Self-renewal is defined as the ability to proliferate in an undifferentiated state and pluripotency as the capacity to differentiate into cells of the three germ layers, i.e., ectoderm, mesoderm, and endoderm. PSCs are derived from early embryos as embryonic stem cells (ESCs) or are produced by reprogramming somatic cells into induced pluripotent stem cells (iPSCs). In mice, PSCs can be
doi:10.3390/app10248861
fatcat:nprfmc6cyvbwxm2nsno62lixma