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Optimal Intervention in Semi-Markov-Based Asynchronous Probabilistic Boolean Networks
2018
Complexity
Synchronous probabilistic Boolean networks (PBNs) and generalized asynchronous PBNs have received significant attention over the past decade as a tool for modeling complex genetic regulatory networks. From a biological perspective, the occurrence of interactions among genes, such as transcription, translation, and degradation, may require a few milliseconds or even up to a few seconds. Such a time delay can be best characterized by generalized asynchronous PBNs. This paper attempts to study an
doi:10.1155/2018/8983670
fatcat:4zcgzt5ddbeb3kydxt3k2y4fui