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Gastroretentive drug delivery system of levofloxacin hemihydrate
International Journal of Health Sciences
The aim of the studies to formulate and develop mucoadhesive microcapsules of levofloxacin hemihydrates by using the mucoadhesive polymers for the treatment of H. pylori infection. Methods: Microspheres were prepared by Ionotropic gelation technique. To achieve the mucoadhesive and extended release property in this study, sodium alginate, chitosan and calcium chloride for formulating levofloxacin hemihydrate microcapsules. In vitro drug release and in-vitro mucoadhesiveness. Results: To achievedoi:10.53730/ijhs.v6ns10.13326 fatcat:5wkvxdeapbeixd5e533ctnggxe