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Long term bed rest with and without vibration exercise countermeasures: Effects on human muscle protein dysregulation
2010
Proteomics
The present investigation, the first in the field, was aimed at analyzing differentially, on individual samples, the effects of 55 days of horizontal bed rest, a model for microgravity, on myosin heavy and myosin light chain isoforms distribution (by SDS) and on the proteome (by 2-D DIGE and MS) in the vastus lateralis (VL), a mixed type II/I ($50:50%) head of the quadriceps and in the calf soleus (SOL), a predominantly slow ($35:65%) twitch muscle. Two separate studies were performed on six
doi:10.1002/pmic.200900817
pmid:20957755
fatcat:mrmwlfbb7rhj7oqnecuit65gne