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Multiple-channel detection of cellular activities by ion-sensitive transistors
2018
Japanese Journal of Applied Physics
An ion-sensitive field-effect transistor to record cellular activities was demonstrated. This field-effect transistor (bio transistor) includes cultured cells on the gate insulator instead of gate electrode. The bio transistor converts a change in potential underneath the cells into variation of the drain current when ion channels open. The bio transistor has high detection sensitivity to even minute variations in potential utilizing a subthreshold swing region. To open ion channels, a reagent
doi:10.7567/jjap.57.04fm03
fatcat:nfrxhbgwifa3beiq2j4ep4h5di