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Three-Dimensional Cell Culture Matrices: State of the Art
2008
Tissue engineering. Part B, Reviews
Traditional methods of cell growth and manipulation on 2-dimensional (2D) surfaces have been shown to be insufficient for new challenges of cell biology and biochemistry, as well as in pharmaceutical assays. Advances in materials chemistry, materials fabrication and processing technologies, and developmental biology have led to the design of 3D cell culture matrices that better represent the geometry, chemistry, and signaling environment of natural extracellular matrix. In this review, we
doi:10.1089/teb.2007.0150
pmid:18454635
fatcat:vk3f6tupsvagfatwhuisxy6h3q