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Bone demineralization, dehydration, and stasis put astronauts at an increased risk of forming kidney stones in space. The incidence of kidney stones and the potential for a mission-critical event are expected to rise as expeditions become longer and immediate transport to Earth becomes more problematic. At the University of Washington, we are developing an ultrasound-based stone management system to detect stones with S-mode ™ ultrasound imaging, break stones with burst wave lithotripsy (BWL ™doi:10.1016/s2468-8967(16)30018-0 pmid:29034360 pmcid:PMC5640155 fatcat:alvuczgzejbdbhdbnmbpfgikiy