Rosmarinic Acid as a Novel Agent in the Treatment of Autoimmune Disease

Jill Stansbury, Paul Saunders, David Winston, Eugene R. Zampieron
2012 Journal of Restorative Medicine  
Rosmarinic acid has been shown to selectively induce T cell apoptosis in aberrant lymphocytes, but not normal/quiescent T cells. Rosmarinic acid also reduces gamma interferon driven T cell responses and reduces interleukin production following T cell stimulation. Furthermore, rosmarinic acid affects signal transduction inside T cells by affecting specific tyrosine kinase enzymes inside the cell. By direct effects on T cells as well as other anti-inflammatory and antioxidant effects, rosmarinic
more » ... cid may be a safe and valuable tool for reducing autoimmune inflammation. It may also be safe and advantageous to use in tandem with pharmaceutical treatment of autoimmune diseases.
doi:10.14200/jrm.2012.1.1013 fatcat:tmhczj4zc5cvfbgsjicamoj33e