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Chemical and biological investigations of a toxic plant from Central Africa, Magnistipula butayei subsp. montana
2006
Journal of Ethnopharmacology
A4cigni. §/i.pw/cz b4iJciyei. subsp. mon/ancï (CAErysobcz/cïnczceOEe) is known, in the Great Lakes Region, to possess toxicological properties. In this paper, we investigated the acute toxicity (dose levels 50-1600 mgAEg) of its aqueous extract, administered orally to adult Wi. §/c]r rats. This study demonstrated that the freeze-dried aqueous extract (5%, w/w) possesses high toxicity. The extract caused hypothermia, neurological disorders, including extensor reflex of maximal convulsfve
doi:10.1016/j.jep.2005.08.019
pmid:16174557
fatcat:fmk7ba336bbnpodg4zw7geqjju