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CD133 does not enrich for the stem cell activity in vivo in adult mouse prostates
Stem Cell Research
CD133 is widely used as a marker for stem/progenitor cells in many organ systems. Previous studies using in vitro stem cell assays have suggested that the CD133-expressing prostate basal cells may serve as the putative prostate stem cells. However, the precise localization of the CD133-expressing cells and their contributions to adult murine prostate homeostasis in vivo remain undetermined. We show that loss of function of CD133 does not impair murine prostate morphogenesis, homeostasis anddoi:10.1016/j.scr.2016.03.003 pmid:27010655 fatcat:cgh7hmdu7fhdjcawjbi2nehv6i