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International Journal of Current Trends in Pharmaceutical Research
Migraine is a syndrome that affects a significant fraction of the world population, with a higher prevalence in women (15%) than in men (6%). Approximately 70% of patients have a first-degree relative with a history of migraine. Migraine occurs with increased frequency in patients with mitochondrial disorders, such as Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis and Stroke like Episodes. Based on the clinical features of migraine, three distinct phases can be discerned: an initiatingfatcat:7kfveukm6fdo3ce7ygrj2tkyqq