Friedel-Crafts alkylation of aromatic derivatives using deep eutectic solvent ZnCl2/ethylene glycol

Hung Thi Anh Hang, Phuong Hoang Tran
2018 Science and Technology Development Journal - Natural Sciences  
Deep eutectic solvent ZnCl2/ethylene glycol synthesized from ethylene glycol and zinc chloride was investigated for the Friedel-Crafts alkylation of benzene derivatives with benzyl bromide at 120oC under solvent-free microwave irradiation. The reaction was carried out under mild condition with high conversion, high regioselectivity, and short reaction time. Moreover, the catalyst can be recovered and reused without significant loss of the catalytic activity. This method can be applied on industrial processes in the future.
doi:10.32508/stdjns.v1it5.544 fatcat:7hcv6gjsfjdi3beirzpoq3euqu