Synthesis of some bis- and mono-2-hydroxybenzoic acid derivatives and the determination of their acidity constants

Evgenija Djurendic, Gyöngyi Vastag, Teréziám Surányi, Mirjana Popsavesé, Katarina Penov-Gasi
2000 Journal of the Serbian Chemical Society  
Several bis-and mono-2-hydroxybenzoicacid derivatives were synthesized by thereactionofmethyl2-hydroxybenzoatewithsomealcohols(diols,polyolsandamino alcohols) and their acidity constants were determined in 60 % aqueous ethanol by the potentiometric titration method. It has been shown that the biochemical behaviour of these compounds is greatly dependent on their acidity. It appears that the ester derivativesareweakeracidsthantheamidederivativesand,therefore,canbepotentiallymore involved in the
more » ... rocesses of metal ions transport in plants, whereas the introduction of OH and CH 3 groups has a very small effect on the biochemical properties. : 2-hydroxybenzoicacid derivatives, synthesis, acidity constants.
doi:10.2298/jsc0010681d fatcat:v4gnegylerhszhjjqlsfjvhovq