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A fully automatic technique for precise localization and quantification of Amyloid-β PET scans
2019
Journal of Nuclear Medicine
Spatial heterogeneity in the accumulation of amyloid-β plaques throughout the brain during asymptomatic as well as clinical stages of Alzheimer disease calls for precise localization and quantification of this protein using PET imaging. To address this need, we have developed and evaluated a technique that quantifies the extent of amyloid-β pathology on a millimeter-by-millimeter scale in the brain with unprecedented precision using data from PET scans. Methods: An intermodal and intrasubject
doi:10.2967/jnumed.119.228510
pmid:31171596
pmcid:PMC6894379
fatcat:ad43nmfrqzfzthwk7u6i43v6du