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Segmentation of DNA into Coding and Noncoding Regions Based on Recursive Entropic Segmentation and Stop-Codon Statistics
2004
EURASIP Journal on Advances in Signal Processing
Heterogeneous DNA sequences can be partitioned into homogeneous domains that are comprised of the four nucleotides A, C, G, and T and the stop codons. Recursively, we apply a new entropic segmentation method on DNA sequences using Jensen-Shannon and Jensen-Rényi divergences in order to find the borders between coding and noncoding DNA regions. We have chosen 12and 18-symbol alphabets that capture (i) the differential nucleotide composition in codons and (ii) the differential stop-codon
doi:10.1155/s1110865704309212
fatcat:utn4ileicfd2vk4lx5wxxph73a