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SNIPE score can capture prodromal Alzheimer's in cognitively normal subjects
[article]
2019
bioRxiv
pre-print
Capturing early changes in the brain related to Alzheimer's disease may lead to models that successfully predict cognitive decline and the eventual onset of dementia, well ahead of onset of clinical symptoms. In this study we used both hippocampal volume and our hippocampal driven SNIPE score to show which marker better captures Alzheimer's related changes in a large dataset of normal controls (N=515) from the ADNI study, comparing controls that remain cognitively stable and controls that
doi:10.1101/541854
fatcat:tnbpvdqrtvhe3k2kclnfkenq6u