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Effect of Rifaximin on Hepatic Fibrosis in Bile Duct-ligated Rat Model
2017
Korean Journal of Gastroenterology
Background/Aims: The translocation of bacteria and their lipopolysaccharides from the gut can promote fibrosis in cirrhotic patients. The aim of this study was to investigate the effects of rifaximin on hepatic fibrosis in a bile duct-ligated rat model. Methods: The bile duct ligation (BDL) was carried out for eight days (acute injury model: sham-operated rats [G1], BDL rats [G2], and BDL rats treated with rifaximin [G3]) or 22 days (chronic injury model: sham-operated rats [G4], BDL rats [G5],
doi:10.4166/kjg.2017.70.5.239
pmid:29161793
fatcat:rqlvd7rr3bhdzmvh7ktcya3kq4