Th e aim of our study was to validate the eff ect of radionuclide imaging in early monitoring of the bone' s reconstruction, the animal model of bone defect was made on the rabbits repaired with HA artifi cial bone. Th e ability of bone defect repair was evaluated by using radionuclide bone imaging at , ,  and  weeks postoperatively. Th e results indicate that the experimental group stimulated more bone formation than that of the control group. Th e diff erences of the bone reconstruction

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... bility were statistically signifi cant (p<.). Th e nano-HA artifi cial has good bone conduction, and it can be used for the treatment of bone defects. Radionuclide imaging may be an eff ective and fi rst choice method for the early monitoring of the bone' s reconstruction.