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Serum thyroglobulin antibody levels within or near to the reference range may interfere with thyroglobulin measurement
High concentration of thyroglobulin antibodies (TgAb) is a major limiting factor of thyroglobulin measurements in patients with differentiated thyroid cancer. We investigated whether thyroglobulin antibody added to serum samples could interfere with the thyroglobulin assay. Thyroglobulin levels in serum samples with different concentrations of thyroglobulin were measured by electrochemiluminescence immunoassay before and after the addition of increasing concentrations of thyroglobulin antibodydoi:10.11613/bm.2012.038 fatcat:6u5pqdadcranhfems6bnd3sfai