Nucleotide sequence analysis of a homologue of herpes simplex virus type 1 gene US9 found in the genome of simian herpes B virus

A. M. Killeen, L. Harrington, L. V. M. Wall, D. C. Kelly
1992 Journal of General Virology  
The 10K gene of simian herpes B virus (SHBV) has been located and the nucleotide sequence determined. Its relationship to homologous genes in other herpesviruses has been examined. The SHBV 10K gene exhibits a closer relationship to its homologue in HSV-1 than to those in the other viruses studied. Nucleotide sequence identity of 61% was found between the HSVl and SHBV 10K genes, and 57% identity was found between the corresponding predicted protein Sequences. A comparison of the amino acid
more » ... ences of the herpesvirus 1 OK proteins has revealed a number of conserved features. These are examined in relation to possible functions of the 1 OK proteins. Implications for evolutionary relationships between SHBV and other herpesviruses are discussed.
doi:10.1099/0022-1317-73-1-195 pmid:1309859 fatcat:gbrm5ewl2ngdpa3lyb7j45kdve