The Relation between Glycated Hemoglobin and Severity of Coronary Artery Disease in Non-Diabetic Patients with Acute Coronary Syndrome

Reda Biomy
Journal of Cardiology & Current Research   unpublished
Aim: This study aimed to assess the relationship between HbA1c level and coronary artery disease (CAD) among non-diabetic patients. Methods: One hundred patients with acute coronary syndrome (ACS) who referred to coronary angiography were included. According to American Diabetes Association (ADA7) patients were classified into high risk group (HbA1c 5.7-6.4%) or low risk group (HbA1c <5.7%). The severity of CAD was assessed by Gensini score which allocates a numerical value for the degree of
more » ... or the degree of coronary stenosis and a multiplication factor that depends on lesion location. Results: The level of HbA1c was positively correlated with Gnsini score (r=0.35, P<0.05,). However HbA1c has no significant correlation with either RWMSI (r=-0.09, p>05) or LVEF (r=-0.04, p>0.05). Conclusion: Among non-diabetic patients, higher HbA1c is significantly correlated with the severity of CAD. HbA1c level has a prognostic value to predict the severity of CAD among non-diabetic patients.