Volume-assured pressure support mode plus pirfenidone as resuscitation therapy in patients with exacerbation of idiopathic pulmonary fibrosis

Killen Harold Briones Claudett, Mónica H Briones Claudett, Estupiñan Vargas Domenica, Stalin Rodriguez Garcia, Jaime Benites Solis, Cesar Andrade Cabrera, Michelle Grunauer Andrade
2020 Advances in Respiratory Medicine  
Treatment among advanced stage idiopathic pulmonary fibrosis is quite challenging, especially considering that no major evidence has been released about it. This case report demonstrates and discusses the benefit of non-invasive mechanical ventilation in volume-assured pressure support (AVAPS) mode plus pirfenidone based on the relief of apatient'ssymptoms in combination with high-resolution computed tomography (HRCT) evidence. An 83-year-old female patient with multiple hospital admissions
more » ... in a six-month period initially presented with cardiac symptoms which were later attributed to apossible exacerbation of her primary diagnosis, idiopathic pulmonary fibrosis. The addition of non-invasive mechanical ventilation in AVAPS mode plus pirfenidone can improve the survival rates even in patients with current exacerbations of acute respiratory failure due to idiopathic pulmonary fibrosis.
doi:10.5603/arm.2020.0077 pmid:32383467 fatcat:okya6h64l5erbc2htz2cwfwua4