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The rising threat of antibiotic resistance in Europe and beyond is of increasing concern and is prompting renewed effort to better understand and mitigate their impact. Escherichia Coli blood stream infections are a more major concern in Europe given their incidence and severe associated outcomes. Additionally the level of 3rd generation cephalosporins and carbapenems resistance among those bacteraemias has significantly increased, limiting available treatment options. We estimated the currentdoi:10.1101/052944 fatcat:aglbmrvkxbhuzebzhlv5luq2im