Retrospective allergy diagnosis of lysteriosis and lysteria carrying in animals

Natalia A. Askhatova, Azat M. Alimov, Nadiya R. Kasanova, Elena Y. Mikryukova, R. Nizamov, A. Valiev, A. Taylan, F. Nezhmetdinova, B. Ziganshin
2020 BIO Web of Conferences  
Experimental infections of guinea pigs and rabbits with a sublethal dose of L. monocytogenes pathogen caused an allergic reaction in the form of delayed-type hypersensitivity (DTHS), which was detected by an intradermal allergy test with a Listeriose allergen. The status of DTHS in guinea pigs and rabbits was recorded for a longer time as compared to specific antibodies. A positive allergic reaction correlated with listeria, which was confirmed by the isolation of a Listeria culture 6 months
more » ... culture 6 months after infection of rabbits with a virulent Listeria strain. The research findings showed that an intradermal allergy test with a developed Listeria allergen allows a retrospective diagnosis of Listeriosis and Listeria carrying. A specific feature of Listeria allergen was established through an intradermal provocative test in animals sensitized by heterogeneous microorganisms (Salmonella and E. coli).
doi:10.1051/bioconf/20202700054 fatcat:gymq7knv7zcgnisumn7ri57mye