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Pelletization by Extrusion-Spheronization: A detailed review Pelletization by Extrusion-Spheronization-A detailed review
2012
All Res. J. Biol
unpublished
Oral multiparticulate drug systems (e.g. pellets, granules) in comparison to single unit dosage forms offer biopharmaceutical advantages in terms of more even and predictable drug distribution in the enteric system. Extrusion spheronization is one of the most commonly used techniques in the formulation of such multiparticulate beads and pellets providing sustained and controlled release or modified release drug delivery. This review outlines the various steps involved in the extrusion
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