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The attachment of N-glycans to nascent glycoproteins in the endoplasmic reticulum (ER) is intimately related to glycoprotein biogenesis. Processing of N-linked oligosaccharides begins in the ER and participates in glycoprotein folding and assembly. The elucidation of N-glycan processing mechanisms in the ER is uncovering their role in glycoprotein biosynthesis.doi:10.1093/glycob/cwg075 pmid:12736198 fatcat:q6hxfwnf7rcdxbqq4runsa3cnm