Synthesis, coordination and biological aspects of organotin(IV) derivatives of 4-[(2,4-dinitrophenyl)amino)]-4-oxo-2-butenoic acid and 2-{[(2,4-dinitrophenyl)amino]carbonyl}benzoic acid

Khadija Shahid, Saira Shahzadi, Saqib Ali
2009 Journal of the Serbian Chemical Society  
New series of organotin(IV) complexes of aniline derivatives, R 2 SnL 2 and R 3 SnL [where R = Me, n-Bu, Ph, n-Oct] have been synthesized by the reaction of HL 1 and HL 2 with respective organotin halides or oxides. Experimental details for the preparation and characterization (including elemental analysis, IR and multinuclear NMR ( 1 H-, 13 C-and 119 Sn-) spectra in CDCl 3 and EI mass spectra of both series are provided. The binding sites of the ligands were identified by means of FTIR
more » ... copic measurements. It was found that in all cases the organotin(IV) moiety reacts with the oxygen of COOgroup to form new complexes. In the diorganotin complexes, the COOgroup is coordinated to the organotin(IV) centres in a bidentate manner in the solid state. The 119 Sn NMR data and the n J( 13 C-119/117 Sn) coupling constant support the tetrahedral coordination geometry of the organotin complexes in non-coordinating solvents. Biological activities (antibacterial, antifungal, cytotoxicity, antileishmanial and insecticidal) of these compounds are also reported.
doi:10.2298/jsc0902141s fatcat:wskvioamcvbmjcxbtcf6ywp6nm