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Do more complex organisms have a greater proportion of membrane proteins in their genomes?
2000
Proteins: Structure, Function, and Bioinformatics
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One may speculate that higher organisms require a proportionately greater abundance of membrane proteins within their genomes in order to furnish the requirements of differentiated cell types, compartmentalization, and intercellular signalling. With the recent availability of several complete prokaryotic genome sequences and sufficient progress in many eukaryotic genome sequencing projects, we seek to test this hypothesis. Using optimized hydropathy analysis of proteins in several, diverse
doi:10.1002/(sici)1097-0134(20000601)39:4<417::aid-prot140>3.0.co;2-y
pmid:10813823
fatcat:gylcfbgmdvchjc7g3p6sgpo6aq