Anaesthetic Management of Siblings having Xeroderma Pigmentosum: A Rare Presentation

Neeraj Kumar
2016 Journal of Anesthesia & Critical Care Open Access  
Xeroderma Pigmentosum (XP) is a rare autosomal recessive disease which causes skin pigmentation with precancerous lesions and neurological abnormalities. These manifestations are due to a cellular hypersensitivity to ultraviolet (UV) radiation leading to a defect in repair of DNA by the process of nucleotide excision repair (NER) mechanism. Here, we are reporting a child with XP scheduled for excision of basal cell carcinoma over the central area of scalp under general anaesthesia.
doi:10.15406/jaccoa.2015.04.00129 fatcat:d4xj2dh42rbxhaewp425qw7q7u