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BMC Microbiology A first insight into the genetic diversity of Mycobacterium tuberculosis in Dar es Salaam, Tanzania, assessed by spoligotyping

Vegard Eldholm, Mecky Matee, Sayoki Mfinanga, Manfred Heun, Ulf Dahle
2006 BMC Microbiology   unpublished

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Tanzania has a high tuberculosis incidence, and genotyping studies of Mycobacterium tuberculosis in the country are necessary in order to improve our understanding of the epidemic. Spoligotyping is a potentially powerful genotyping method due to fast generation of genotyping results, high reproducibility and low operation costs. The recently constructed SpolDB4 database and the model-based program 'Spotclust' can be used to assign isolates to families, subfamilies and variants. The results of a study can thus be analyzed in a global context.
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Vegard Eldholm, Mecky Matee, Sayoki Mfinanga, Manfred Heun, Ulf Dahle. "BMC Microbiology A first insight into the genetic diversity of Mycobacterium tuberculosis in Dar es Salaam, Tanzania, assessed by spoligotyping." BMC Microbiology (2006)