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The earthworms numbers and biodiversities are considered as an indicator of soil nature and fertility. Earthworms are very important soil organisms that aid in the decomposition of plant litter. In recent era earthworm obtain more attention in agriculture practices, so that in the present work to determined the comparative effects of nitenpyram and spinetoram on total amount of protein and cholinesterase activity of Pheretima posthuma Kinberg (Order: Haplotaxida and Family: Megaseolecide )doi:10.52763/pjsir.biol.sci.61.2.2018.103.111 fatcat:x4xi5b3sojbn7dvyptyf4p2ope