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1P091 Liposome Display : Directed evolution of membrane protein, alpha hemolysin, by using liposome and cell-free translation system(01F. Protein:Engineering,Poster)
1P091 膜たんぱく質の進化工学手法「リポソームディスプレイ法」の構築と実践 : リポソームと無細胞翻訳系によるα-ヘモリシンのin vitro分子進化(01F. 蛋白質:蛋白質工学/進化工学,ポスター,日本生物物理学会年会第51回(2013年度))
2013
Seibutsu Butsuri
1P091 膜たんぱく質の進化工学手法「リポソームディスプレイ法」の構築と実践 : リポソームと無細胞翻訳系によるα-ヘモリシンのin vitro分子進化(01F. 蛋白質:蛋白質工学/進化工学,ポスター,日本生物物理学会年会第51回(2013年度))
In vitro methods have enabled the rapid and efficient evolution of proteins and successful generation of novel and highly functional proteins. However, the available methods deal only with globular proteins (e.g., antibodies and enzymes), and not membrane proteins. Here, we report the development of a method named liposome display that can evolve the properties of membrane proteins entirely in vitro. This method, which involves in vitro protein synthesis inside liposomes was applied to the
doi:10.2142/biophys.53.s121_1
fatcat:qiywfxhynzcunksvsh3j5tvb2y