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Pathology of Variant Creutzfeldt-Jakob Disease
Variant Creutzfeldt-Jakob disease (CJD) is a novel form of human prion disease that appears to result from oral infection by the bovine spongiform encephalopathy (BSE) agent. Variant CJD is also unique in human prion diseases in that infectivity and accumulation of the diseaseassociated isoform of prion protein are readily detectable outside the central nervous system, perhaps reflecting the peripheral pathogenesis of this disorder following an oral infection with BSE. The neuropathologicaldoi:10.1007/4-431-29402-3_1 fatcat:v6tbrws5b5c5bhhnv5kgyt673a