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ACTILIFE TABLET AND GREEN TEA EXTRACT ACT SYNERGISTICALLY TO PROTECT RAT LIVER AGAINST PARACETAMOL TOXICITY
2017
unpublished
In the present study protective effect of Actilife tablets (AT) and Green tea extract (GTE) against paracetamol induced hepatotoxicity was evaluated individually and in combination. Rats are pretreated with AT (50 and 100 mg/kg, p.o), GTE (5 and 10 mg/kg, p.o), and combination formulation, ATG (40 and 80 mg/kg, p.o), for 14 days. On day 14 paracetamol was administered (2.5 g/kg, p.o) and after 48 h serum was analyzed for ASAT, ALAT, ALP and TP. The liver tissue was analyzed for SOD, catalase,
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