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Redundancy based detection of sequence polymorphisms in expressed sequence tag data using autoSNP
2003
Bioinformatics
AutoSNP is a program to detect single nucleotide polymorphisms (SNPs) and insertion/deletion polymorphisms (indels) in expressed sequence tag (EST) data. The program uses d2cluster and cap3 to cluster and align EST sequences, and uses redundancy to differentiate between candidate SNPs and sequence errors. Candidate polymorphisms are identified as occurring in multiple reads within an alignment. For each candidate SNP, two measures of confidence are calculated, the redundancy of the polymorphism
doi:10.1093/bioinformatics/btf881
pmid:12584131
fatcat:pjxd7eetvvfqlbk6bbyjodpa6m