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Lipid Lowering Therapy with Combination of Niacin and Statin in Women: Age-Related Endothelial Effects
ISRN Vascular Medicine
Background. Many women remain at risk for cardiac events despite treatment to reduce low-density lipoprotein cholesterol (LDL-C). We hypothesized that for postmenopausal women treated with niacin in addition to statin vascular function will improve. Methods. We conducted a randomized, double-blind, placebo-controlled trial of 16 weeks of niacin (N) versus placebo (PL) in 43 women (mean age, 67±9 years) previously on statin therapy. Study outcomes included lipoprotein levels, vasculardoi:10.1155/2013/168504 fatcat:t2hldsb3lrcv5eousd6nuakwdm