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Streptococcal Meningitis Reveals the Presence of Residual Streptococci and Down-Regulated Aquaporin 4 in the Brain
The pathology of streptococcal meningitis is poorly understood, even though streptococcal infection induces meningitis. The aim of this study was to clarify the relationship between streptococcal meningitis and aquaporin 4 (AQP4) in the mouse brain. After Streptococcus suis infection, the streptococcal number was calculated, and AQP4 mRNA expression in the brain was quantified at 2 and 7 days after infection. At 7 days post-infection, mice with neurological symptoms showed significantly higherdoi:10.21203/rs.3.rs-529424/v1 fatcat:azz2hngjkbaifpf5wordvt6uei