Novel poly(ADP-ribose) polymerase inhibitor veliparib: biophysical studies on its binding to calf thymus DNA

Hongqin Yang, Peixiao Tang, Bin Tang, Yanmei Huang, Xinnuo Xiong, Hui Li
2017 RSC Advances  
Veliparib, an new anticancer drug in the class of poly (ADP-ribose) polymerase inhibitors, intercalates partially and binds to ctDNA and induces moderate conformational perturbation of the DNA.
doi:10.1039/c6ra28213j fatcat:56oj4d7ksvc5jaqorkdxajc7sa