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HBV and HCV infections are among the most important global health problems; both represent also the leading cause of cirrhosis and HCC worldwide. HBV treatment cannot be considered cure but effective viral suppression can be achieved and remains the current principal goal of therapy. Talking about HCV treatment today equals to talking about total cure of the patient, with treatments of very high SVR rates, shorter if not shortest duration, minimal risk for resistance, pangenotypic anddoi:10.4081/thal.2014.4870 doaj:242b2cb2777247d9ab22c4f4ca6ee618 fatcat:26mpoye2krf4hd6msysch4pkh4