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This thesis includes two parts. Part I, 'Development of a peptide microarray method to study post-translational modifications' and part II, 'Toxicity of galectin-9 toward KRAS mutated CRC cells: pathway elucidation'. Part I aimed to study the posttranslational modifications (PTMs), O-GlcNAcylation/ de- O-GlcNAcylation, phosphorylation/ dephosphorylation, crosstalk between de-O-GlcNAcylation and dephosphorylation and finally O-GlcNAcylation of JAK2 JH1 kinase using short peptide substratesdoi:10.33540/1663 fatcat:mrje2vdmjfabvbdaesjch3micq