Improving the value of clinical research through the use of Common Data Elements

Jerry Sheehan, Steven Hirschfeld, Erin Foster, Udi Ghitza, Kerry Goetz, Joanna Karpinski, Lisa Lang, Richard P Moser, Joanne Odenkirchen, Dianne Reeves, Yaffa Rubinstein, Ellen Werner (+1 others)
2016 Clinical Trials  
The use of Common Data Elements (CDEs) can facilitate cross study comparisons, data aggregation and meta-analyses, simplify training and operations, improve overall efficiency, promote interoperability between different systems, and improve the quality of data collection. A CDE is a combination of a precisely defined question (variable) paired with a specified set of responses to the question that is common to multiple datasets or used across different studies. CDEs, especially when they
more » ... to accepted standards, are identified by research communities from variable sets currently in use or are newly developed to address a designated data need. There are no formal international specifications governing the construction or use of CDEs. Consequently, CDEs tend to be made available by research communities on an empiric basis.
doi:10.1177/1740774516653238 pmid:27311638 pmcid:PMC5133155 fatcat:47lpdw3udzh6helkiv6vzgo4dq