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slope conductance of IK(ACh) averaged 42±3 pS (n=28) in HF and 44±2 pS (n=4) in donors, and mean open lifetime was 1.3+±0.3 milliseconds (n=24) in HF and 1.5+±0.4 milliseconds (n=4) in donors. These values were virtually identical in the two groups (not significantly different, NS), although both single IKI and IK(ACh) channel densities were less in HF. Channel open probability of IK(ACh) was also less in HF (4.0+1.2%, n=24) than in donors (6.8+1.1%, n=3, P<.01). The concentration of ACh atdoi:10.1161/01.cir.90.5.2213 pmid:7955176 fatcat:r3qqdsnt4jdjfdr352whkvp5wm