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Cross-protection elicited by primary and booster vaccinations against Japanese encephalitis: A two-year follow-up study
Background: The inactivated Vero cell-derived vaccine (JE-VC, IXIARO) has replaced the traditional mouse brain-derived preparations (JE-MB) in travelers' vaccinations against Japanese encephalitis. We showed recently that a single JE-VC dose efficiently boosts immunity in JE-MB-primed vaccinees, and that JE-VC elicits cross-protective immunity against non-vaccine genotypes, including the emerging genotype I. While these studies only provided short-term data, the present investigation evaluatesdoi:10.1016/j.vaccine.2013.10.055 pmid:24176496 fatcat:2iecwobejfegtlv6actvjqzjwu