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Protein-protein interaction prediction for targeted protein degradation
[article]
2022
bioRxiv
pre-print
Protein-protein interactions (PPIs) play a fundamental role in various biological functions; thus, detecting PPI sites is essential for understanding diseases and developing new drugs. PPI prediction is of particular relevance for the development of drugs employing targeted protein degradation, as their efficacy relies on the formation of a stable ternary complex involving two proteins. However, experimental methods to detect PPI sites are both costly and time-intensive. In recent years,
doi:10.1101/2022.02.25.481776
fatcat:dloli6x57rafpgtnv44kx66n5q