Arch Dis Child 2012;97(Suppl 2):A1-A539 A335 Abstracts Conclusion E. Coli and AR EOS were predominant in preterm infants with GA ≤ 35 weeks. GA ≤ 35 weeks is an independent predicted factor of AR EOS. INCIDECE OF NEONATAL SEPSIS AND/OR MENINGITIS Beckground and aim Infections are important cause of mortality and morbidity in the neonatal period. The purpose in this retrospective study was to identifications the bacterial microorganisms caued neonatal sepsis and/or meningitis in the all newborns

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... hospitalized in the Center of Neonatology , during the period of 2002, 2003 and 2004. Method We used clinical, microbiological, laboratory and radiology methods. Results 2086 infants were treated at the Center of Neonatology during the period of 2002-2004. Infants born at term (NT) were 1391, and infants born preterm (NPT) were 682. In the group of infants born at term In 528 with proven infections (omphalitis, cutaneus infections, mastitis, conjunctivitis, otitis media, infectio tracti urinary, pneumonia, diarrhea), 58 were diagnosed and treated for sepsis and/or meningitis (10.9%). Dominant pathogens responsabile for sepsis and/or meningitis were: Staphylococcus k.n (41.3%) i Staphylococcus Aureus (19%), E.Coli (5, 3%), then with equally frequency SGB, Streptococcus alfa hemolyticus rupe A, Streptococcus pneumoniae, Enterococcus, L .Monocytogenes, Klebsiella pneumoniae, (each one 1.7%). Meningitis were proven in 16 TNB or 27.6 per cent. In the group of infants born preterm In 98 PNB with proven infections (omphalitis, cutaneus infections, conjunctivitis, infectio tracti urinary, pneumonia, diarrhea), 30 PTB were diagnosed and treated for sepsis and/or meningitis (30.6%). Dominant pathogens responsabile for sepsis and/or meningitis were: Staphylococcus aureus (26.6%), Staphylococcus Co negative (20.0%), Klebsiella pnaeumonia (20.0%), Serratia marscensens (13.3%). Meningitis were proven in 7 PNB or 23.3% per cent. Conclusions Preterm infants have 3 fold higher incidence of serious neonatal infections sepsis and/or meningitis. SYSTEMIC CANDIDIASIS: IMPACT OF THE SELECTIVE PROPHYLAXIS WITH FLUCONAZOLE IN RN < 1500GR