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Sulfation ofN-Acetylglucosamine by Chondroitin 6-Sulfotransferase 2 (GST-5)
Journal of Biological Chemistry
Based on sequence homology with a previously cloned human GlcNAc 6-O-sulfotransferase, we have identified an open reading frame (ORF) encoding a novel member of the Gal/GalNAc/GlcNAc 6-O-sulfotransferase (GST) family termed GST-5 on the human X chromosome (band Xp11). GST-5 has recently been characterized as a novel GalNAc 6-O-sulfotransferase termed chondroitin 6-sulfotransferase-2 (Kitagawa, H., Fujita, M., Itio, N., and Sugahara K. (2000) J. Biol. Chem. 275, 21075-21080). We have coexpresseddoi:10.1074/jbc.m006414200 pmid:10956661 fatcat:um3uuqpt35au5b3ugykq5hntnu