Hypothyroidism is a common thyroid disorder. It affects people all over the world irrespective of age, sex, race, and level of wealth and education. Prevalence of hypothyroidism is 2-4% in women in their reproductive age groups. Hypothyroidism can affect fertility due to anovulatory cycles, luteal phase defects, hyperprolactinemia and sex hormone imbalances. The objective of present study is to do an assessment regarding the prevalence of clinical/sub-clinical hypothyroidism in infertile women

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... nd the treatment responses for hypothyroidism on infertility. Methods: A total of 120 infertile women were found who, visited, the infertility clinic for the first time. Reports of clinical parameter such as obtained for, thyroid stimulating hormone (TSH), prolactin (PRL) and estrogen (E 2 ). Analysis were done at early stage of infertility checkup, instead of straight away going for more expensive tests or invasive procedures. Results: Finding, suggest an increased level of TSH, PRL AND E2 in infertile women of middle age (30 -40 yrs). Conclusion: Identification of hypothyroidism and hyperprolactinemia during early and late reproductive stage stages can be preventive in infertile females hence such screening should be mandatory in the primary phage of such females.