Diabetes and impaired glucose metabolism is associated with more cold-related cardiorespiratory symptoms

Tiina Maria Ikäheimo, Jari Jokelainen, Juhani Hassi, Liisa Hiltunen, Sirkka Keinänen-Kiukaanniemi, Tiina Laatikainen, Pekka Jousilahti, Markku Peltonen, Leena Moilanen, Juha Saltevo, Simo Näyhä
2017 Diabetes Research and Clinical Practice  
Artikkelit Terveystieteiden tiedekunta 2017 Diabetes and impaired glucose metabolism is associated with more cold-related cardiorespiratory symptoms Ikäheimo TM Elsevier BV info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion © Elsevier BV CC BY-NC-ND https://creativecommons.org/licenses/by-nc-nd/4.0/ Word count: 4721 words, including narrative text, three tables and figure legends (excluding references, abstract), + 1 figure and 1 supplementary figure ABSTRACT Aims: Diabetes
more » ... d impaired glucose metabolism cause metabolic, neural and circulatory disturbances that may predispose to adverse cooling and related symptoms during the cold season. This study assessed the prevalence of cold-related cardiorespiratory symptoms in the general population according to glycaemic status. Methods: The study population consisted of 2436 men and 2708 women aged 45-74 years who participated in the National FINRISK cold sub-studies in 2002 and 2007. A questionnaire assessed cold-related symptoms (respiratory, cardiac, peripheral circulation ). Glycaemic status was determined based on fasting blood glucose, oral glucose tolerance tests or reported diagnosis of diabetes and categorized into normal glucose metabolism, impaired fasting blood glucose, impaired glucose tolerance, screening-detected type 2 diabetes and type 2 diabetes. Results: Type 2 diabetes was associated with increased odds for cold-related dyspnoea [Adjusted OR 1.72 (95% CI, 1.28-2.30)], chest pain [2.10 (1.32-3.34)] and respiratory symptoms [1.85 (1.44-2.38)] compared with normal glucose metabolism. Screened type 2 diabetes showed increased OR for cold-related dyspnoea [1.36 (1.04-1.77)], cough [
doi:10.1016/j.diabres.2017.04.022 pmid:28521195 fatcat:n5c26eswsrginiu5v4cpm2ihe4